Myotonic dystrophy is

(1) Autosomal recessive trait

(2) Autosomal dominant trait

(3) X- linkeddominant trait

(4) X- linked recessive trait

Subtopic:  Non - Disjunction & Aneuploidy |
 80%
From NCERT
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Boy born to a physically normal couple has been diagnosed with a genetic disorder, this could be

(1) Y- linked trait.

(2) Autosomal dominant trait

(3) X- linked dominant trait

(4) X- linked recessive trait

Subtopic:  Sex Linked Recessive Inheritance |
 76%
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Which of the following disorder is associated with Queen Victoria?

(1) Sickle cell anaemia

(2) Haemophilia

(3) Huntington's Disease

(4) Myotonic dystrophy

Subtopic:  Mendelian Disorders: Hemophilia |
 93%
From NCERT
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Which of the following is least probable? 

(1) Female child with Sickle cell anaemia

(2) Male child with haemophilia

(3) Carrier female for haemophilia

(4) Female child with haemophilia

Subtopic:  Sex Linked Recessive Inheritance |
 79%
From NCERT
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Which of the following disorder can’t be transmitted from a single diseased parent? 

(1) Sickle cell anaemia

(2) Haemophilia

(3) Colour Blindness

(4) Myotonic dystrophy

Subtopic:  Mendelian Disorders: Sickle Cell Anemia |
 59%
From NCERT
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Which of the following genotypes could cause Sickle cell anaemia? 

(1) Hbˢ + Hbᴬ

(2) Hbᴬ+ Hbᴬ

(3) Hbˢ + Hbˢ

(4) Both ‘A’ and ‘C’.

Subtopic:  Mendelian Disorders: Sickle Cell Anemia |
 74%
From NCERT
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Sickle cell anaemia is caused by

(1) Substitution of valine by glutamic acid at 6th position in the polypeptide.

(2) Substitution of valine by glycine at 4th position in the polypeptide.

(3) Substitution of glutamic acid by valine at 4th position in the polypeptide.

(4) Substitution of glutamic acid by valine at 6th position in the polypeptide.

Subtopic:  Mendelian Disorders: Sickle Cell Anemia |
 84%
From NCERT
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Elongated sickle like structure of RBC is produced by

(1) Platelets deposition on the outer surface of RBC

(2) Reduced surface tension

(3) Polymerisation of mutant haemoglobin under high oxygen tension.

(4) Polymerisation of mutant haemoglobin under low oxygen tension.

Subtopic:  Mendelian Disorders: Sickle Cell Anemia |
 82%
From NCERT
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Sickle cell anaemic person will have 

(1) Abnormal beta globin chain and sickle shaped RBC

(2) Normal beta globin chain and sickle shaped RBC

(3) Abnormal beta globin chain and biconcave RBC

(4) Normal beta globin chain and biconcave RBC

Subtopic:  Mendelian Disorders: Sickle Cell Anemia |
 85%
From NCERT
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Mental retardation is associated with

(1) Klinefelter’s syndrome

(2) Haemophilia

(3) Cystic fibrosis

(4) Phenylketonuria

Subtopic:  Mendelian Disorders |
 73%
From NCERT
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