The ADA deficiency is because of

(1) Substitution

(2) Inversion

(3) Deletion

(4) Insertion

Subtopic:  Gene Therapy |
 88%
From NCERT
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The possible treatments of ADA deficiency are

(1) Bone Marrow Transplantation

(2) Enzyme replacement Therapy

(3) Both

(4) None of these

Subtopic:  Gene Therapy |
 93%
From NCERT
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Which of the following therapies for ADA deficiency are not completely curative?

(1) Bone Marrow Transplantation

(2) Enzyme replacement Therapy

(3) Both A and B

(4) Both are completely curative

Subtopic:  Gene Therapy |
 81%
From NCERT
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The first step of gene therapy would be

(1) Culture of the lymphocytes from patient's blood

(2) Using vector for transmitting gene

(3) cDNA was prepared

(4) cDNA was inserted directly into the cells

Subtopic:  Gene Therapy |
 82%
From NCERT
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The last step of gene therapy would be

(1) The corrected lymphocytes are returned to the patients

(2) Culture of lymphocytes of the patient

(3) Introduction of correct gene in cultured cells

(4) Removal of corrected lymphocytes from culture

Subtopic:  Gene Therapy |
 79%
From NCERT
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The permanent cure of gene therapy can be

(1) Cells isolated from bone marrow in an adult were cultured and transformed with corrected gene

(2) Cells isolated from thymus in an adult were cultured and transformed with corrected gene

(3) Cells isolated from bone marrow in an embryo were cultured and transformed with corrected gene

(4) Genes isolated from bone marrow were introduced into the cells at early embryonic stage

Subtopic:  Gene Therapy |
 77%
From NCERT
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Conventional methods are not

(1) Serum analysis

(2) Urine analysis

(3) For early detection

(4) Both B and C

Subtopic:  Molecular Diagnosis |
 76%
From NCERT
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Early diagnosis of a disease cannot be served by

(1) ELISA

(2) PCR

(3) Recombinant DNA Technology

(4) X-Ray

Subtopic:  Molecular Diagnosis |
 87%
From NCERT
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PCR will allow to detect genetic defects but doesn't involve which of the following steps.

(1) Probing with radioactive molecule

(2) Hybridization

(3) Autoradiography

(4) Antigen antibody interaction

Subtopic:  Molecular Diagnosis |
 73%
From NCERT
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ELISA involves

(1) Detection by the presence of antigens

(2) Detection by the presence of antibodies synthesized against pathogen

(3) Both A and B

(4) Only detection of the outer coat of pathogen

Subtopic:  Molecular Diagnosis |
 90%
From NCERT
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