Adult human RBCs are enucleate. Which of the following statement(s) is/are most appropriate explanation for this feature?
| (I) | They do not need to reproduce. |
| (II) | They are somatic cells. |
| (III) | They do not metabolise. |
| (IV) | Their internal space is available for oxygen transport. |
| 1. | Only (IV) | 2. | Only (I) |
| 3. | (I), (III) and (IV) | 4. | (II) and (III) |