a. | C-peptide is found attached with both A and B chains of insulin with the help of disulphide bonds. |
b. | In 1983, both A and B chains were produced by introducing alien genes in plasmid of same E.coli by Eli Lilly. |
c. | A-peptide and B-peptide of insulin are interconnected by peptide bonds in mature insulin. |
d. | Insulin from an animal source may cause allergy or other types of reactions in some diabetic patients. |
Assertion (A): | Insulin used for diabetes was earlier extracted from the pancreas of slaughtered cattle and pigs but now it is not used. |
Reason (R): | Aarti along with some other patients took insulin injections in which insulin was from an animal source and they manifested an allergic response to that. |
1. | Both (A) and (R) are True and (R) is the correct explanation of (A). |
2. | Both (A) and (R) are True but (R) is not the correct explanation of (A). |
3. | (A) is True but (R) is False. |
4. | (A) is False but (R) is True. |
With regard to insulin, choose the correct options:
a: | C-peptide is not present in mature insulin. |
b: | The insulin produced by rDNA technology has C-peptide. |
c: | The pro-insulin has C-peptide. |
d: | A-peptide and B-peptide of insulin are interconnected by disulphide bridges. |
1. | (a), (c) and (d) only | 2. | (a) and (d) Only |
3. | (b) and (d) only | 4. | (b) and (c) only |