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Q. No.Which of the following statements are correct with reference to a transcription unit?
Choose the correct answer from the options given below
| A. | transcription unit in DNA is defined primarily by three regions : promoter, structural gene and terminator. |
| B. | The promoter is said to be located towards the 5'-end of the structural gene. |
| C. | The promoter is a DNA sequence that provides binding site for RNA polymerase. |
| D. | The promoter defines the template and coding strands. |
| E. | The terminator is located towards the 3'-end of the coding strand and it defines the end of the process of transcription. |
| 1. | A, B, C, D and E | 2. | B, C, D and E only |
| 3. | A, C, D and E only | 4. | A, B, C and D only |
Subtopic: Transcription |
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Arrange the following steps of DNA fingerprinting in a correct sequence.
Choose the correct answer from the options given below :
| A. | Isolation of DNA and its digestion by restriction endonucleases. |
| B. | Hybridisation using a labelled VNTR probe. |
| C. | Transferring of separated DNA fragments to synthetic membranes. |
| D. | Detection of hybridised DNA fragments by autoradiography. |
| E. | Separation of DNA fragments by electrophoresis. |
| 1. | A, E, C, B, D | 2. | A, E, B, C, D |
| 3. | A, B, D, C, E | 4. | A, D, B, E, C |
Subtopic: DNA Fingerprinting |
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Which of the following statements are correct with reference to packaging of DNA helix?
Choose the correct answer from the options given below:
| A. | Histones are organized to form a unit of eight molecules called histone octamer. |
| B. | Histones are negatively charged basic proteins. |
| C. | Histones are rich in the basic amino acid residues - lysine and arginine. |
| D. | The positively charged DNA is wrapped around the histone octamer to form nucleosome. |
| E. | The packaging of chromatin at higher levels requires an additional set of proteins called non-histone chromosomal proteins. |
Choose the correct answer from the options given below:
| 1. | A, B and D only | 2. | A, C and E only |
| 3. | C, D and E only | 4. | B, D and E only |
Subtopic: DNA Packaging |
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In the lac operon, the z gene codes for:
| 1. | transacetylase | 2. | the repressor of lac operon |
| 3. | permease | 4. | beta-galactosidase |
Subtopic: Gene Regulation: Lac Operon |
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Which chromosome in the human genome has the highest number of genes?
| 1. | Chromosome 1 | 2. | Chromosome 10 |
| 3. | Chromosome X | 4. | Chromosome Y |
Subtopic: Human Genome Project |
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Match List-I with List-II:
Choose the correct answer from the options given below:
| List-I | List-II | ||
| A. | Alfred Hershey and Martha Chase | I. | Streptococcus pneumoniae |
| B. | Euchromatin | II. | Densely packed and dark- stained |
| C. | Frederick Griffith | III. | Loosely packed and light-stained |
| D. | Heterochromatin | IV. | DNA as genetic material confirmation |
| 1. | A-IV, B-III, C-I, D-II | 2. | A-III, B-II, C-IV, D-I |
| 3. | A-II, B-IV, C-I, D-III | 4. | A-IV, B-II, C-I, D-III |
Subtopic: Miscellaneous |
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Which of the following are the post-transcriptional events in an eukaryotic cell?
Choose the correct answer from the options given below:
| A. | Transport of pre-mRNA to the cytoplasm prior to splicing |
| B. | Removal of introns and joining of exons. |
| C. | Addition of methyl group at 5' end of hnRNA. |
| D. | Addition of adenine residues at 3' end of hnRNA. |
| E. | Base pairing of two complementary RNAs. |
| 1. | B, C, E only | 2. | C, D, E only |
| 3. | A, B, C only | 4. | B, C, D only |
Subtopic: Transcription |
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Given below are two statements :
| Statement I : | In the RNA world, RNA is considered the first genetic material evolved to carry out essential life processes. RNA acts as a genetic material and also as a catalyst for some important biochemical reactions in living systems. Being reactive, RNA is unstable. |
| Statement II : | DNA evolved from RNA and is a more stable genetic material. Its double helical strands being complementary, resist changes by evolving repairing mechanism. |
| 1. | Statement I is correct but Statement II is incorrect |
| 2. | Statement I is incorrect but Statement II is correct |
| 3. | Both Statement I and Statement II are correct |
| 4. | Both Statement I and Statement II are incorrect |
Subtopic: RNA world |
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Given below are two statements :
In the light of the above statements, choose the most appropriate answer from the options given below:
| Statement I: | Transfer RNAs and ribosomal RNA do not interact with mRNA. |
| Statement II: | RNA interference (RNAi) takes place in all eukaryotic organisms as a method of cellular defence. |
In the light of the above statements, choose the most appropriate answer from the options given below:
| 1. | Statement I is correct but Statement II is incorrect |
| 2. | Statement I is incorrect but Statement II is correct |
| 3. | Both Statement I and Statement II are correct |
| 4. | Both Statement I and Statement II are incorrect |
Subtopic: Translation Mechanism | Transcription |
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Who proposed that the genetic code for amino acids should be made up of three nucleotides?
| 1. | Jacque Monod | 2. | Franklin Stahl |
| 3. | George Gamow | 4. | Francis Crick |
Subtopic: Genetic Code |
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