A. | This disorder was first described by Langdon Down (1866). |
B. | Such an individual has overall masculine development. However, the feminine development is also expressed. |
C. | The affected individual is short statured. |
D. | Physical, psychomotor and mental development is retarded. |
E. | Such individuals are sterile. |
1. | A and E only | 2. | A and B only |
3. | C and D only | 4. | B and E only |
1. | Thalassemia | 2. | Down's syndrome |
3. | Turner's syndrome | 4. | Klinefelter's syndrome |
Match List-I with List-II
List-I | List-II | ||
(a) | Haemophilia | (i) | Inborn error of metabolism which lacks an enzyme that converts phenylalanine into tyrosine |
(b) | Down's Syndrome | (ii) | Sex-linked recessive disorder; a defect in blood coagulation |
(c) | Phenylketonuria | (iii) | Presence of additional copy of X-chromosome (44+XXY) |
(d) | Klinefelter's Syndrome | (iv) | Additional copy of chromosome number 21 |
Choose the correct answer from the options given below:
(a) | (b) | (c) | (d) | |
1. | (ii) | (iv) | (i) | (iii) |
2. | (iv) | (ii) | (i) | (iii) |
3. | (ii) | (iii) | (i) | (iv) |
4 | (i) | (ii) | (iii) | (iv) |
What is the genetic disorder in which an individual has an overall masculine development gynaecomastia, and is sterile?
1. | Down's syndrome | 2. | Turner's syndrome |
3. | Klinefelter's syndrome | 4. | Edward syndrome |
Match the items of Column - I with Column - II :
Column-I | Column-II | ||
(a) | XX-XO method of sex determination | (i) | Turner's syndrome |
(b) | XX-XY method of sex Determination | (ii) | Female heterogametic |
(c) | Karyotype-45 | (iii) | Grasshopper |
(d) | ZW-ZZ method of Sex Determination | (iv) | Female homogametic |
Select the correct option from the following:
(a) | (b) | (c) | (d) | |
1. | (ii) | (iv) | (i) | (iii) |
2. | (i) | (iv) | (ii) | (iii) |
3. | (iii) | (iv) | (i) | (ii) |
4. | (iv) | (ii) | (i) | (iii) |
In which genetic condition, each cell in the affected person, has three sex chromosomes XXY?
1. Thalassemia
2. Klinefelter's Syndrome
3. Phenylketonuria
4. Turner's Syndrome
A human female with Turner's syndrome:
1. has 45 chromosomes with XO
2. has one additional chromosome.
3. exhibit male character
4. is able to produce children with a normal husband.
1. | Klinefelter's syndrome-44 autosomes + XXY |
2. | Colourblindness – Y-linked |
3. | Erythroblastosis foetalis-- X-linked |
4. | Down syndrome--44 autosomes + XO |
In Drosophila the XXY condition leads to femaleness whereas in human beings the same condition leads to Klinefelter's syndrome in males. It proves:
1. | In human beings, the Y chromosome is active in sex determination. |
2. | Y chromosome is active in sex determination in both human beings and Drosophila. |
3. | In Drosophila Y-chromosome decides femaleness. |
4. | The Y chromosome of man has genes for the syndrome. |