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Q. No.In the human genome, the chromosomes with the most and the fewest genes located on them respectively are:
1. 1 and Y 2. X and Y 3. 21 and X 4. 11 and Y
Subtopic: Human Genome Project |
74%
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Identify the correct statement:
| 1. | The coding strand in a transcription unit is copied to an mRNA. |
| 2. | Split gene arrangement is characteristic of prokaryotes. |
| 3. | In capping, methylguanosine triphosphate is added to the 3' end of hnRNA. |
| 4. | RNA polymerase binds with the Rho factor to terminate the process of transcription in bacteria. |
Subtopic: Transcription |
66%
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NEET - 2021
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What catalyzes the peptide bond formation in prokaryotes?
1. Proteases
2. A ribozyme
3. Sigma subunit of RNA polymerase
4. Rho factor proteins
Subtopic: Gene Regulation: Introduction |
68%
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The genetic material for the first life on the earth was probably:
| 1. | ds DNA | 2. | ss DNA |
| 3. | Protein | 4. | RNA |
Subtopic: DNA vs RNA as Genetic Material |
89%
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Transfer of electrophoresis-separated DNA fragments to a filter membrane and subsequent fragment detection by probe hybridization is called as:
| 1. | DNA profiling | 2. | PCR |
| 3. | Southern blotting | 4. | Elution |
Subtopic: DNA Fingerprinting |
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Avery, MacLeod, and McCarty used DNase in their experiment because:
| 1. | It enabled them to isolate pure DNA samples. |
| 2. | It enabled them to isolate pure protein samples. |
| 3. | This allowed them to demonstrate that removing the DNA prevents transformation. |
| 4. | It made sure that RNA will always be present when they attempted to transform the R strain. |
Subtopic: Search for Genetic Material |
84%
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Although gene expression in eukaryotes can take place at multiple levels. The most common level of gene expression would be:
| 1. | transcriptional level (formation of the primary transcript) |
| 2. | processing level (regulation of splicing) |
| 3. | transport of mRNA from the nucleus to the cytoplasm |
| 4. | translational level |
Subtopic: Gene Regulation: Introduction | Gene Regulation in Eukaryotes |
66%
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Which fact regarding the Human Genome Project is not correct?
| 1. | The Human Genome Project was a 13-year project coordinated by the U.S. Department of Energy and the National Institute of Health. |
| 2. | Many non-human model organisms, such as bacteria, yeast, Caenorhabditis Elegans (a free-living non-pathogenic nematode), Drosophila (the fruit fly), plants (rice and Arabidopsis), etc., have also been sequenced. |
| 3. | The sequence of chromosome 1 was completed only in May 2016 (this was the last of the 24 human chromosomes – 22 autosomes and X and Y – to be sequenced). |
| 4. | The fragments were sequenced using automated DNA sequencers that worked on the principle of a method developed by Frederick Sanger. |
Subtopic: Human Genome Project |
88%
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Identify the correctly matched pairs:
| A: | Expressed Sequence Tags | Fragments of mRNA sequences derived through single sequencing reactions performed on randomly selected clones from cDNA libraries. |
| B: | Sequence Annotations | The process of marking specific features in a DNA, RNA, or protein sequence with descriptive information about structure or function. |
| 1. | Only A | 2. | Only B |
| 3. | Both A and B | 4. | Neither A nor B |
Subtopic: Human Genome Project |
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What will not be true regarding polymorphism in DNA?
| 1. | Polymorphism (variation at the genetic level) arises due to mutations. |
| 2. | Allelic sequence variation has traditionally been described as a DNA polymorphism if more than one variant (allele) at a locus occurs in the human population with a frequency greater than 1.00. |
| 3. | The probability of polymorphic variation to be observed in non-coding DNA sequence would be higher as mutations in these sequences may not have any immediate effect/impact on an individual’s reproductive ability. |
| 4. | For evolution and speciation, polymorphisms play a very important role. |
Subtopic: DNA Fingerprinting |
79%
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