The essential difference between DNA replication in eukaryotes and prokaryotes will be:
1. A high % of AT base pairs in Ori region of eukryotic DNA.
2. Bidirectional movement of replication fork in eukaryotes.
3. Eukaryotes contain several different DNA polymerases.
4. Telomerase required to replicate the ends of eukaryotic chromosomes.

Mutations can lead to incorporation of wrong amino acid into the polypeptide chain. This is least likely to occur when there is:
1. a change in the wobble base of the codon.
2. a mistake in amino acid attachment to the tRNA.
3. a change in the third base of the anticodon.
4. a gene mutation involving the first base of the codon.

The one gene — one enzyme hypothesis basically means that:
1. Every gene encodes a protein.
2. Each structural gene encodes an essential metabolic enzyme.
3. Each structural protein is encoded by a single gene.
4. Genes are always expressed as enzymes

A ribosomal binding site in bacterial and archaeal messenger RNA, generally located around 8 bases upstream of the start codon AUG is called as:
1. Shine-Dalgarno sequence.
2. Kozak consensus sequence.
3. Sorting signals.
4. Prinbow box.

Match the following RNA polymerases with their transcribed products:

Select the correct option from the following:

Which scientist experimentally proved that DNA is the sole genetic material in bacteriophage?

1. Beadle and Tatum

2. Messelson and Stahl

3. Hershey and Chase

4. Jacob and Monod

All the following regarding RNA splicing are correct except:
1. Some introns can splice themselves out.
2. Splicing is required for some tRNAs.
3. The final step of splicing is formation of a phosphodiester linkage.
4. Introns often have a specific function after they are removed.

The use of proflavin in his experiments enabled Francis Crick to determine that the genetic code is a triplet code because:
1. It causes mutations in DNA.
2. It can cause large deletions in DNA.
3. It causes single insertions or deletions in DNA sequences.
4. It can be lethal.

Oculocutaneous albinism is a genetic disorder in human characterized by lack of pigmentation of skin. This can be caused by all the following except:
1. Lack of an enzyme that synthesizes the pigment molecules.
2. Lack of a protein that transports the pigment molecules to the appropriate location.
3. Lack of a receptor protein that allows the pigment to be taken up into appropriate cells.
4. Exposer to colder environment for a long period

Two amino acids will differ from each other in their properties because they have different:
1. The amino group.
2. The carboxyl group.
3. The R group.
4. Peptide bonds.