On examining a sample of human DNA, it was found that it contains approximately 24 % thymine. Which of the following would be true based on this finding?

1. The amount of adenine in a similar sample of DNA from any human being will be approximately 24 %.

2. The amount of adenine in a similar sample of DNA from any living being will be approximately 24 %.

3. The amount of adenine in a similar sample of DNA from any eukaryotic cell will be approximately 24 %.

4. The amount of adenine in a similar sample of DNA from any mammal will be approximately 24 %.

Subtopic:  Search for Genetic Material:I | Search for Genetic Material: II |
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If the sequence of nitrogen bases of the coding strand of DNA in a transcription unit is:

5' -ATGAATG-3',

the sequence of bases in its RNA transcript would be;

1. 5'-AUGAAUG-3'

2. 5'-UACUUAC-3'

3. 5'-CAUUCAU-3'

4. 5'-GUAAGUA-3'

Subtopic:  Transcription: I | Transcription:II |
 62%
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The RNA polymerase holoenzyme transcribes:

1. the promoter, structural gene and the terminator region

2. the promoter and the terminator region

3. the structural gene and the terminator region

4. the structural gene only.

Subtopic:  Transcription: III |
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To initiate translation, the mRNA first binds to:

1. The smaller ribosomal sub-unit,

2. The larger ribosomal sub-unit

3. The whole ribosome

4. No such specificity exists.

Subtopic:  Translation | Translation Mechanism |
 85%
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In E.coli, the lac operon gets switched on when:

1. lactose is present and it binds to the repressor

2. repressor binds to operator

3. RNA polymerase binds to the operator

4. lactose is present and it binds to RNA polymerase

Subtopic:  Gene Regulation: Lac Operon |
 80%
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Deoxyribonucleotides in a ds DNA are held by:
I. Phosphodiester.
II. Hydrogen.
III. Ionic.
1. I and II only
2. I and III only
3. II and III only
4. I, II and III

Subtopic:  DNA Double Helix |
 77%

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All the following will not be applicable to DNA replication in prokaryotes except:
1. It begins at several places along the chromosome.
2. It begins at the origin and travels in both directions.
3. It begins at the origin and travels around the chromosome back to the origin.
4. It begins at a GC rich region of the chromosome.

Subtopic:  DNA Replication |

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Constitutive heterochromatin includes:
1. The Barr body.
2. A region of active gene expression.
3. Telomeres.
4. Both 1 and 2.

Subtopic:  The DNA |

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Proof reading, the error-correcting processes, first proposed by John Hopfield and Jacques Ninio, during DNA replication takes place by:
1. Endonuclease cleavage.
2. Exonuclease cleavage.
3. Methylation.
4. An induced-fit phenomenon.

Subtopic:  DNA Replication: I |

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Identify the incorrect statement regarding structure of DNA:
1. Pitch is 3.4nm and 10 base pairs.
2. The two strands are antiparallel.
3. Each pair of nucleotides is held together by three hydrogen bonds.
4. The diameter of the molecule is a uniform 2nm.

Subtopic:  DNA Double Helix |
 83%
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