In a test cross, the plant expressing the dominant phenotype is crossed with the plant:

1. Which is heterozygous dominant
2. Which is heterozygous recessive
3. Which is homozygous recessive
4. Which is homozygous dominant

Subtopic:  Monohybrid Cross: 1 |
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Identify the incorrect statement:

1. In addition to recombination, the mutation is another phenomenon that leads to variation in DNA.
2. Chromosomal aberrations are commonly observed in cancer cells.
3. A classical example of a point mutation is sickle cell anemia.
4. Non-ionising radiations cannot be mutagens.
Subtopic:  Mutation |
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What is incorrect for Hemophilia?

1. In this disease, a single protein that is a part of the cascade of proteins involved in the clotting of blood is affected.
2. In an affected individual, a simple cut will result in non-stop bleeding.
3. The heterozygous female (carrier) for haemophilia may transmit the disease to her sons.
4. The possibility of a female becoming haemophilic is extremely rare because the mother of such a female has to be hemophilic and the father should be a carrier.
Subtopic:  Mendelian Disorders: Hemophilia |
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Mendel’s work remained unrecognised till 1900. Which of the following was not a reason for this?

1. His work was widely publicised and it brought a bad name to Mendel.
2. His concept of factors as stable and discrete units that did not ‘blend’ was not accepted.
3. His approach of using mathematics to explain biological phenomena was unacceptable.
4. He could not provide any physical proof for the existence of factors or say what they were made of.
Subtopic:  Introduction to Genetics: 1 | Introduction to Genetics: 2 |
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Sickle cell anaemia results from:
1. A chromosomal aberration
2. Non-disjunction of autosome
3. A point mutation
4. Blood transfusion reaction

Subtopic:  Mendelian Disorders: Sickle Cell Anemia |
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What is the ratio of a typical monohybrid test cross?

1. 2 : 1 2. 3 : 1
3. 1: 2 : 1 4. 1 : 1
Subtopic:  Monohybrid Cross: Further Understanding |
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In complete dominance, the recessive allele with respect to the dominant allele:
1. Produces no product
2. Produces a different product
3. Produces half the product
4. Produces no product or a non-functional product

Subtopic:  Dominance Deviation from Mendel: 1 |
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Genes tightly linked on the same chromosome show:

1.Very high recombination2.Independent assortment
3.Very low recombination4.50 % recombination

Subtopic:  Recombination & Gene Mapping |
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Which of the following amino acid substitution in the beta chain of the haemoglobin molecule leads to the development of sickle cell anaemia?
1. Arginine by tyrosine
2. Tyrosine by phenylalanine
3. Valine by Glutamic acid
4. Glutamic acid by Valine

Subtopic:  Mendelian Disorders: Sickle Cell Anemia |
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In Phenylketonuria,

I. Phenylpyruvic acid and other derivatives are accumulated in the brain resulting in mental retardation.
II. These are also excreted through urine because of their poor absorption by the kidney.

1.Only I is correct2.Only II is correct
3.Both are correct4.Both are incorrect

Subtopic:  Mendelian Disorders |
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