| Assertion (A): | RNAi is an RNA-dependent gene silencing process. |
| Reason (R): | The RNAi pathway is a naturally occurring process found in many eukaryote cells. |
| 1. | Both (A) and (R) are True and (R) correctly explains (A) |
| 2. | Both (A) and (R) are True and (R) does not correctly explain (A) |
| 3. | (A) is True; (R) is False |
| 4. | (A) is False; (R) is True |
| I: | Gene therapy involves the introduction of a functional gene into the cells of an individual to treat genetic disorders. |
| II: | RNA interference (RNAi) is a technique used to silence specific genes by degrading their structural genes located on template DNA. |
| III: | Transgenic organisms are those that have been genetically modified to express desirable traits. |
| (A) | It is a method of cellular defense in all prokaryotic organisms. |
| (B) | This method has been used to make nematode resistant tobacco plants. |
| (C) | It is a post translational method of silencing of genes. |
| I: | RNAi takes place in all eukaryotic organisms as a method of cellular defense. |
| II: | RNAi involves silencing of a specific mRNA due to a complementary dsDNA molecule. |
| Statement I: | RNA interference takes place in all eukaryotic organisms as method of cellular defense. |
| Statement II: | RNAi involves the silencing of a specific mRNA due to a complementary single stranded RNA molecule that binds and prevents translation of mRNA |