Glucose is absorbed in the small intestine and from the lumen passes first to epithelial cell and then to the blood. What would be true regarding absorption of glucose?

1. It enters from the epithelial cell to the blood vessel against its concentration gradient

2. The movement of glucose from the lumen into the epithelial cell requires a facilitated transport protein

3. The movement of glucose from the lumen into the epithelial cell requires an active transport protein and an energy source

4. The movement of glucose from the epithelial cell into the blood vessel requires an active transport protein and an energy source