Q. No.When a cell has stalled DNA replication fork, which checkpoint should be predominantly activated?
1.
G1/S
2.
G2 /M
3.
M
4.
Both G2/M and M
| 1. | G1/S | 2. | G2 /M |
| 3. | M | 4. | Both G2/M and M |
Anaphase Promoting Complex (APC) is protein degradation machinery necessary for proper mitosis of animal cells. If APC is defective in a human cell, which of the following is expected to occur?
1. Chromosomes will be fragmented
2. Chromosomes will not segregate
3. Recombination of chromosome arms will occur
4. Chromosomes will not condense
Match the following Column-I with Column-II.
| Column-I | Column-II | ||
| A. | Synapsis aligns homologous chromosomes |
(i) | Anaphase II |
| B. | Synthesis of RNA and protein | (ii) | Zygotene |
| C. | Action of enzyme recombinase | (iii) | G2 - phase |
| D. | Centromeres do not separate, but chromosomes move towards opposite poles | (iv) | Anaphase I |
| (v) | Pachytene |
| 1. | A-(ii), B-(i), C-(iii), D-(iv) | 2. | A-(ii), B-(iii), C-(v), D-(iv) |
| 3. | A-(i), B-(ii), C-(v), D-(iv) | 4. | A-(ii), B-(iii), C-(iv), D-(v) |
A somatic cell that has just completed the S-phase of its cell cycle, as compared to a gamete of the same species has:
| 1. | twice the number of chromosomes and twice the amount of DNA |
| 2. | the same number of chromosomes but twice the amount of DNA |
| 3. | twice the number of chromosomes and four times the amount of DNA |
| 4. | four times the number of chromosomes and twice the amount of DNA |
During which phase(s) of the cell cycle, amount of DNA in a cell remains at 4 C level if the initial amount is denoted as 2C:
| 1. | G0 and G1 | 2. | G1 and S |
| 3. | Only G2 | 4. | G2 and M |
A stage in cell division is shown in the figure. Select the answer which gives the correct identification of the stage with its characteristics:
|
1. |
Late anaphase |
Chromosomes move away from the equatorial plate, Golgi complex not present |
|
2. |
Cytokinesis |
Cell plate formed, mitochondria distributed between two daughter cells |
|
3. |
Telophase |
Endoplasmic reticulum and nucleolus not reformed yet |
|
4. |
Telophase |
Nuclear envelop reforms, Golgi complex reforms |
Cells in phase:
1. terminate the cell cycle
2. exit the cell cycle
3. enter the cell cycle
4. suspend the cell cycle
After meiosis I, the resultant daughter cells have
| 1. | same amount of DNA as in the parent cell in S |
| 2. | twice the amount of DNA in comparison to haploid |
| 3. | same amount of DNA in comparison to haploid gamete |
| 4. | four times the amount of DNA in comparison to haploid gamete |
| 1. | 4 | 2. | 32 |
| 3. | 8 | 4. | 16 |
| a. | Synapsis of homologous chromosomes |
| b. | Chromosomes become gradually visible under a microscope |
| c. | Crossing over between non-sister chromatids of homologous chromosomes |
| d. | Terminalisation of chiasmata |
| e. | Dissolution of synaptonemal complex |
Choose the correct answer from the options given below:
| 1. | (a), (b), (c), (d), (e) | 2. | (b), (c), (d), (e), (a) |
| 3. | (b), (a), (c), (e), (d) | 4. | (a), (c), (d), (e), (b) |
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