Find the incorrect statement.
1. Gene therapy is a genetic engineering technique
used to treat disease at molecular level by
replacing defective genes with normal genes
2. Calcitonin is a medically useful recombinant
product in the treatment of infertility
3. Bt toxin is biodegradable insecticide obtained
from Bacillus thuringiensis
4. Trichoderma sp. is a biocontrol agent for fungal
diseases of plants

Which of the following is removed during maturation of insulin?

1. A chain

2. B chain

3. C chain

4. Disulphide bond 

Select the correct statement:

Transgenic animals are those which have

1. Foreign DNA in some of its cells

2. Foreign DNA in all its cells

3. Foreign RNA in all its cells

4. DNA and RNA both in the cells

Which of the following is correct about probe?
A. It is ssDNA or ssRNA.
B. Used to detect gene of interest from gene library.
C. Used to detect mutations in genes in suspected
cancer patients.
D. Used to detect HIV in suspected AIDS patients.

1. A only
2. A and B
3. A, B and C
4. A,B,C and D

When DNA is transcribed into mRNA, usually the mRNA remains single-stranded, but in some cases a RNA can be made that is complementary to the mRNA. This is called __________ and its main function is to _______:

1. Antisense RNA, block gene expression

2. Antisense RNA, amplify mRNA

3. Antisense RNA, enhance translation

4. Reverse transcription, enhance translation

In biotechnology transgenic animals are used for
I. Study of disease.
II. To obtained human protein.
III. Vaccine safety for humans.
IV. To know the carcinogenicity of any chemicals.

1. I, II, III and IV 
2. III and IV only
3. I, III and IV 
4. I and II only

From RNA interference technique
1. Toxins are made to kill soil parasites.
2. Made crops more tolerant to abiotic stresses.
3. Plants are made resistant to soil parasites.
4. Plants are developed to get the enhanced nutritional
value of food

Read the following four statements (A-D) about certain mistakes in two of them

(A) The first transgenic buffalo, Rosie produced milk which was human alpha-lactal bumin enriched.
(B) Restriction enzymes are used in isolation of DNA from other macro-molecules.
(C) Downstream processing is one of the steps of rDNA technology.
(D) Disarmed pathogen vectors are also used in transfer of r-DNA into the host.

Which are the two statements having mistakes?
1. Statement (B) and (C)
2. Statement (C) and (D)
3. Statement (A) and (C)
4. Statement (A) and (B)

A person received a blood transfusion and he suspects
that the donor’s blood was not properly tested. The
recipient’s blood does not have any anti HIV antibodies
as yet. Which of the following tests would be of
diagnostic value?

1. ELISA

2. Southern blot

3. PCR

4. Northern blot