The largest known human gene is

(1) Dystrophin protein gene on X chromosome

(2) Sry gene on Y chromosome

(3) Dystropin protein gene on Y chromosome

(4) Sry gene on X chromosome

Isotopes used in proving semiconservative replication of DNA were:

(1) ¹⁴N ¹⁴C            

(2) ¹⁴N ¹⁵N            

(3) ¹⁴N ³¹P             

(4) ¹⁴C ³¹P

Column-I                                               Column-II
I. Genome of ϕ 174 bacteriophage           A. Ribozyme, RNAase
II. Purine                                               B. 5386 Nucleotides
III. Catalytic RNA                                   C. Adenine and Guanine
IV. Any chemical change in DNA              D. Mutation
The correct match is:
(1) I - D, II - B, III - A, IV - C                 

(2) I - B, II - A, III - D, IV - C

(3) I - D, II - C, III - A, IV - B                 

(4) I - B, II - C, III - A, IV - D

Column-I                                        Column-II
I. Operator site                               A. Binding site for RNA polymerase
II. Promoter site                              B. Binding site for repressor molecule
III. Structural gene                          C. Codes for enzyme protein
IV. Regulator gene                          D. Code for repressor molecules
The correct match is:
(1) I - B, II - A, III - C, IV - D         

(2) I - B, II - A, III - D, IV - C

(3) I - D, II - C, III - A, IV - B         

(4) I - B, II - C, III - A, IV - D

In chromosome, DNA is associated with:

A. Negatively charged proteins       B. Positively charged proteins

C. Neutral proteins                        D. NHC protein

(1) B, D                

(2) A, B, C, D        

(3) B, C, D            

(4) A, B, C

Heterochromatin:

A. Is more densely packed      B. Is stains dark

C. Is transcriptionally active    D. Is transcriptionally inactive

(1) A, C                

(2) A, B, C, D        

(3) B, C, D            

(4) A, B, D

In 1953, James Watson and F. Crick proposed the Double Helix model of DNA and got Nobel Prize. Their model of DNA was based on:
A. X-ray diffraction of DNA produced by M. Wilkins and R. Franklin
B. Griffith’s experiment.
C. Hershey - Chase experiment
D. Chargaff’s rule of base equivalence (A + G / T + C = 1)

(1) A, D             
(2) A, B, C, D           
(3) B, C, D             
(4) A, B, C

DNA polymerase:
A. Is the main enzyme for RNA synthesis
B. Is DNA dependent DNA polymerizing enzyme
C. Is a highly efficient enzyme
D. Is catalyzes a reaction with a high degree of accuracy
(1) C, D             

(2) A, B, C, D               

(3) B, C, D             

(4) A, B, C

In eukaryotes the gene expression is regulated at:
A. Transcriptional level
B. Processing level
C. Transport of mRNA from nucleus to the cytoplasm
D. Translational level
(1) A, C               

(2) A, B, C, D                 

(3) B, C, D                     

(4) A, B, C

Characteristic(s) of most DNA is / are:
A. A pairs with T by 2 hydrogen bonds.
B. Antipolarity of complementary chains
C. 20Aº diameter
D. 10 bps/turn 
(1) A, C                 

(2) A, B, C, D                     

(3) B, C, D                 

(4) A, B, C