Fredrick Griffith accidentally discovered transformation when attempting to develop a vaccine for pneumonia. He injected mice with samples from S-strain (virulent) and/or R-strain (nonvirulent) pneumococci bacteria (Sterptococcus pneumoniae). Which of the following results is NOT consistent with Griffith's experiments?

1. injected S-strain; mouse dies. 

2. injected R-strain; mouse lives. 

3. injected heat-killed S-strain; mouse lives. 

4. injected mixture of heat-killed S-strain and live R-strain; mouse lives. 

Which scientists first gave experimental evidence that DNA is the genetic material?

The function of the rho protein is 

1. to help terminate translation

2. to help RNA polymerase bind to the DNA

3. to help RNA polymerase find a promoter

4. to help terminate transcription

Genetic information in a DNA molecule is coded in the:

1. Sequence of nucleotides

2. Base pairings 

3. Proportion of each base present

4. The turning pattern of the helix

In general, bacterial genes are regulated at the time of:

1. Transcription

2. Post transcription

3. Translation

4. Post translation  

Match each item in Column I with one item in Column II and chose your answer from the codes given below:

Codes

             I           II         III         IV

(1)         1           2           3           4

(2)         2           1           4           3

(3)         2           1           3           4

(4)         1           2           4           3

Match each item in Column I with one item in Column II and chose your answer from the codes given below:

    Column I                   Column II
  (antibiotic)                    (effect)
I. Tetracycline            1. inhibits binding of aminoacyl tRNA to the ribosome
II. Streptomycin        2. inhibits initiation of translation
III. Chloramphenicol  3. inhibits peptidyl transferase
IV. Erythromycin       4. inhibits translocation of mRNA along with ribosome

Codes:

1. 1 2 3 4

2. 2 1 4 3

3. 2 1 3 4

4. 1 2 4 3

The association of histone H₁ with a nucleosome indicates 

(1) transcription is occuring

(2) DNA replication is occuring

(3) the DNA is condensed into chromatin fibre

(4) the DNA double helix is exposed

The equivalent of a structural gene is

(1) muton

(2) cistron

(3) operon

(4) recon

A molecule that can act as a genetic material must fulfill the traits given below, except

(1) it should be able to express itself in the form of 'Mendelian characters'

(2) it should be able to generate its replica

(3) it should be unstable structurally and chemically

(4) it should provide the scope for slow changes that are required for evolution