Q. No.Which is the basis of genetic mapping of the human genome as well as DNA fingerprinting?
1. Polymorphism in the DNA sequence
2. Single nucleotide polymorphism
3. Polymorphism in the hnRNA sequence
4. Polymorphism in the RNA sequence
What is it that forms the basis of DNA Fingerprinting?
| 1. | The relative difference in the DNA occurrence in blood, skin and saliva |
| 2. | The relative amount of DNA in the ridges and grooves of the fingerprints |
| 3. | Satellite DNA occurs as highly repeated short DNA segments |
| 4. | The relative proportions of purines and pyrimidines in DNA |
Which one of the following is a wrong statement regarding mutations?
| 1. | Cancer cells commonly show chromosomal aberrations |
| 2. | UV and Gamma rays are mutagens |
| 3. | Change in a single base pair of DNA does not cause mutation |
| 4. | Deletion and insertion of base pairs cause frame-shift mutations |
In eukaryotic cell transcription, RNA splicing and RNA capping take place inside the:
1. Nucleus
2. Dictyosomes
3. ER
4. Ribosomes
The lac Operon consists of:
| 1. | One regulatory gene and three structural genes |
| 2. | Two regulatory genes and two structural genes |
| 3. | Three regulatory genes and three structure genes |
| 4. | Four regulatory genes only |
The 3'-5' phosphodiester linkages inside a polynucleotide chain serve to join:
| 1. | One nucleoside with another nucleoside |
| 2. | One nucleotide with another nucleotide |
| 3. | One nitrogenous base with pentose sugar |
| 4. | One DNA strand with the other DNA strand |
In the history of biology, the human genome project led to the development of:
1. Biosystematics
2. Biotechnology
3. Biomonitoring
4. Bioinformatics
The unequivocal proof of DNA as the genetic material came from the studies on:
| 1. | Bacterial virus | 2. | Bacterium |
| 3. | Fungus | 4. | Viroid |
E.coli has only 4.6 × base pairs and completes the process of replication within 18 minutes, then the average rate of polymerization is approximately:
| 1. | 2000 base pairs/second | 2. | 3000 base pairs/second |
| 3. | 4000 base pairs/second | 4. | 1000 base pairs/second |
In the polynucleotide chain of DNA, a nitrogenous base is linked to the –OH of:
| 1. | 2'C pentose sugar | 2. | 3'C pentose sugar |
| 3. | 5'C pentose sugar | 4. | 1'C pentose sugar |
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