The two polypeptide chains of insulin protein are linked together by:

1. disulfide bonds 2. hydrogen bonds
3. covalent bonds 4. ionic bonds
Subtopic:  Gene Therapy | Vaccines |
 94%
From NCERT
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Which of these is an accurate description of gene therapy?

1. A form of site directed mutagenesis.
2. Introduction of cloned genes into living cells to cure disease.
3. Cloning of a disease gene in order to understand the disease.
4. All of these.

Subtopic:  Gene Therapy |
 57%
From NCERT
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Identify the correct statements:
I: ADA deficiency is caused due to the deletion of the gene for adenosine deaminase.
II: Bone marrow transplant and enzyme replacement therapy are completely curative.
III. Lymphocytes transformed with cADA gene are permanent cure for the condition.
 
1. Only I and II 2. Only I
3. Only II and III 4. I, II and III
Subtopic:  Gene Therapy |
 77%
From NCERT
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The first clinical gene therapy trial was given in 1990 to a 4 year girl with:

1. Alpha – 1 antitrypsin deficiency
2. Cystic fibrosis
3. Adenosine deaminase deficiency
4. Chronic myeloid leukemia

Subtopic:  Gene Therapy |
 96%
From NCERT
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The viruses generally used for gene therapy are:

1. ds DNA virus 2. ss DNA virus
3. Reovirus 4. Reterovirus
Subtopic:  Gene Therapy |
 84%
From NCERT
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A possible permanent cure for SCID can be:

1. Enzyme replacement therapy, in which functional ADA is given to the patient by injections.
2. Bone marrow transplantation.
3. A functional ADA cDNA (using a retroviral vector) introduced into lymphocytes.
4. Gene isolated from marrow cells producing ADA is introduced into cells at early embryonic stages.

Subtopic:  Gene Therapy |
 82%
From NCERT
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A probe which is a molecule used to locate homologous sequences in a mixture of DNA or RNA molecules could be:

1. A ssRNA 2. A ssDNA
3. Either RNA or DNA 4. Can be ssDNA but not ssRNA
Subtopic:  Gene Therapy |
 70%
From NCERT
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