Calcium is important in skeletal muscle contraction because it:
1. binds to troponin to remove the masking of active sites on actin for myosin.
2. activates the myosin ATPase by binding to it.
3. detaches the myosin head from the actin filament.
4. prevents the formation of bonds between the myosin cross bridges and the actin filament.
Subtopic:  Excitation Contraction Coupling I | Sliding Filament Theory | Muscle Contraction: Other Considerations |
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Name the ion responsible for unmasking of active sites for myosin for cross-bridge activity during muscle contraction.

(1)  Calcium              

(2)  Magnesium

(3)  Sodium              

(4)  Potassium.

Subtopic:  Sliding Filament Theory |
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