Commonly used vectors for human genome sequencing are

(1) T-DNA

(2) BAC and YAC

(3) Expression vectors

(4) T/A cloning vectors

The full form of ELSI is:

(1) Embedded Low Software Index    

(2) Ear Lung Spleen Immunity

(3) Ethical Legal and Social Issue      

(4) Endonuclease Ligase Surface Immunity

The major approaches used in HGP for identifying genes were

(1) BLAST

(2) Expressed Sequence Tags

(3) Sequence annotation

(4) b and c

In the human being, chromosome 1 has     A      genes and Y has     B     genes.

Select the option which correctly fills A and B.

1. A – 2968, B – 231

2. A – 231, B – 2968

3. A – 2168, B – 321

4. A – 321, B – 2168 

SNP which is pronounced as "snips” stands for:

(1) Small nuclear protein                   

(2) Single nucleotide particle

(3) Single nucleotide polymorphism   

(4) Small nicking points

In HGP, the fragments of DNA were sequenced using automated DNA sequencers. It worked on the principle of a method developed by

1. E.M. Southern

2. Frederick Sanger

3. Craig Venter

4. Wellcome Trust (U.K.)

Which of the following was not the goal of Human Genome Project

1. Identification of human genes

2. human genome sequence determination

3. store information in databases

4. Improve manpower for data analysis

A. DNA polymorphism plays important role in evolution and speciation.
B. 99.9% nucleotides bases are exactly same in all people
C. Chromosome 1 has the fewest genes (23) and Y-chromosomes has most genes (2968)
D. BAC and YAC have been used in Human Genome Project.
(1) All correct                   

(2) All incorrect

(3) A, B, D are correct       

(4) B, C, D are correct

The largest known human gene is

(1) Dystrophin protein gene on X chromosome

(2) Sry gene on Y chromosome

(3) Dystropin protein gene on Y chromosome

(4) Sry gene on X chromosome

The Human Genome Project started in ______and completed, in__________ year respectively.

(1) 1990, 2003

(2) 1993, 2003

(3) 1993, 2006

(4) 1990, 2006