Which of the following technique was used to elucidate the double helix model of DNA?
1. \(\gamma\)-radiation
2. Electromagnetic radiation
3. UV-Vis spectroscopy
4. X-ray diffraction
Subtopic:  DNA Double Helix |
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Read the following statements and choose the set of correct statements: 
 
(a) Euchromatin is loosely packed chromatin.
(b) Heterochromatin is transcriptionally active.
(c) Histone octomer is wrapped by negatively charged DNA in nucleosome.
(d) Histones are rich in lysine and arginine.
(e) A typical nucleosome contains 400 bp of DNA helix.

Choose the correct answer from the options given below:
1. (a), (c), (e) only
2. (b), (d), (e) only
3. (a), (c), (d) only
4. (b), (e) only
Subtopic:  DNA Double Helix | DNA Packaging |
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One of the strands of double stranded DNA has base composition as follows: 15% A, 15% T, 40%G and 30%C. What will be the percentage of these bases in the complementary strand ? 
1. 15% A, 15% T, 30% G , 40% C
2. 15% A, 30% T, 40% G , 15% C
3. 15% A, 15% T, 40% G , 30% C
4. 15% A, 40% T, 15% G , 30% C

Subtopic:  DNA Double Helix |
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If a DNA molecule is shortened by 25 base pairs, how many helical turns will be reduced from its structure?
1. 1
2. 3
3. 2.5
4. 2
Subtopic:  DNA Double Helix |
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Complete the flow chart on central dogma

1. (a) - Replication; (b) - Transcription;
(c) - Translation; (d) -  Protein
2. (a) - Transduction; (b) - Translation;
(c) - Replication;  (d) - Protein
3. (a) - Replication; (b) - Transcription;
(c) - Transduction; (d) - Protein
4. (a) - Transcription; (b) - Replication;
(c) - Transcription; (d) - Transduction
Subtopic:  DNA Double Helix |
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If Adenine makes 30% of the DNA molecule, what will be the percentage of Thymine, Guanine and Cytosine in it?

1. T:30 ; G:20 ; C:20 2. T:20 ; G:25 ; C:25
3. T:20 ; G:30 ; C:20 4. T:20 ; G:20 ; C:30
Subtopic:  DNA Double Helix |
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If the distance between two consecutive base pairs is 0.34 nm and the total number of base pairs of a DNA double helix in a typical mammalian cell is 6.6×109 bp, then the length of the DNA is approximately:

1. 2.5 meters 2. 2.2 meters
3. 2.7 meters 4. 2.0 meters
Subtopic:  DNA Double Helix |
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Which of the following statements is correct?

1. Adenine pairs with thymine through one H-bond.

2. Adenine pairs with thymine through three H-bonds.

3. Adenine does not pair with thymine.

4. Adenine pairs with thymine through two H-bonds.

Subtopic:  DNA Double Helix |
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In the polynucleotide chain of DNA, a nitrogenous base is linked to the –OH of:

1.2'C pentose sugar2.3'C pentose sugar
3.5'C pentose sugar4.1'C pentose sugar

Subtopic:  DNA Double Helix |
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What will be the sequence of mRNA produced by the following stretch of DNA?

3' ATGCATGCATGCATG 5' TEMPLATE STRAND

5' TACGTACGTACGTAC 3' CODING STRAND

1. 3' AUGCAUGCAUGCAUG 5'

2. 5' UACGUACGUACGUAC 3'

3. 3' UACGUACGUACGUAC 5'

4. 5' AUGCAUGCAUGCAUG 3'

Subtopic:  DNA Double Helix |
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