The fact that a purine base always pairs through hydrogen bonds with a pyrimidine base in the DNA double helix leads to:
1. the antiparallel nature
2. the semiconservative nature
3. uniform width throughout DNA
4. uniform length in all DNA
Subtopic:  DNA Double Helix |
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Who amongst the following scientists had no contribution in the development of the double helix model for the structure of DNA?
1. Rosalind Franklin
2. Maurice Wilkins
3. Erwin Chargaff
4. Meselson and Stahl
Subtopic:  DNA Double Helix |
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DNA is a polymer of nucleotides which are linked to each other by 3’-5’ phosphodiester bond. To prevent polymerisation of nucleotides, which of the following modifications would you choose?
1. Replace purine with pyrimidines
2. Remove/Replace 3' OH group in deoxy ribose
3. Remove/Replace 2' OH group with some other group in deoxy ribose
4. Both ‘b’ and ‘c’
 
Subtopic:  DNA Double Helix |
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While analysing the DNA of an organism a total number of 5386 nucleotides were found out of which the proportion of different bases were: Adenine = 29%, Guanine = 17%, Cytosine = 32%, Thymine = 17%. Considering the Chargaff’s rule it can be concluded that:
1. it is a double stranded circular DNA
2. It is single stranded DNA
3. It is a double stranded linear DNA
4. No conclusion can be drawn
Subtopic:  DNA Double Helix |
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