Given below are two statements:
| Assertion (A): | Exposure to small concentrations of CO hinder the ability of Hb to deliver oxygen to the body. |
| Reason (R): | Carboxyhemoglobin \([HbCO]\) forms more readily than does oxyhemoglobin \((HbO_2).\) |
| 1. | Both (A) and (R) are true and (R) is the correct explanation of (A). |
| 2. | Both (A) and (R) are true but (R) is not the correct explanation of (A). |
| 3. | (A) is true but (R) is false. |
| 4. | Both (A) and (R) are false. |
| Assertion (A): | Oxidized hemoglobin carries maximum oxygen in the human blood. |
| Reason (R): | Oxidized hemoglobin has more affinity for oxygen than deoxygenated hemoglobin. |
In the light of the above statements choose the correct answer from the options given below:
| 1. | Both (A) and (R) are true and (R) is the correct explanation of (A). |
| 2. | Both (A) and (R) are true but (R) is not the correct explanation of (A). |
| 3. | (A) is true but (R) is false. |
| 4. | Both (A) and (R) are false. |
Given below are two statements:
| Assertion (A): | Nitric oxide transport by hemoglobin to peripheral tissues is hypothesized to assist oxygen transport in tissues. |
| Reason (R): | Nitric oxide can also be transported by hemoglobin bound to specific thiol groups in the globin protein. |
| 1. | Both (A) and (R) are true and (R) is the correct explanation of (A). |
| 2. | Both (A) and (R) are true but (R) is not the correct explanation of (A). |
| 3. | (A) is true but (R) is false. |
| 4. | Both (A) and (R) are false. |
| Assertion: | Small amounts of CO dramatically reduces hemoglobin's ability to transport oxygen. |
| Reason: | CO competes with oxygen at the heme binding site. |
| 1. | Both assertion and reason are true and the reason is the correct explanation of the assertion. |
| 2. | Both assertion and reason are true but the reason is not the correct explanation of the assertion. |
| 3. | Assertion is true but reason is false. |
| 4. | Both assertion and reason are false. |
| Assertion (A): | The Bohr effect enables the body to adapt to changing conditions and makes it possible to supply extra oxygen to tissues that need it the most. |
| Reason (R): | A lower pH in strenuously metabolizing tissues promotes the dissociation of oxygen from haemoglobin, and allows the surrounding tissues to obtain enough oxygen to meet their demands. |
In the light of the above statements choose the correct answer from the options given below:
| 1. | Both (A) and (R) are true and (R) is the correct explanation of (A). |
| 2. | Both (A) and (R) are true but (R) is not the correct explanation of (A). |
| 3. | (A) is true but (R) is false. |
| 4. | Both (A) and (R) are false. |
| Assertion: | Oxygenation of blood in the lungs displaces carbon dioxide from hemoglobin which increases the removal of carbon dioxide. |
| Reason: | Oxygenated hemoglobin is a better proton donor than deoxygenated hemoglobin. |
| 1. | Both assertion and reason are true and the reason is the correct explanation of the assertion. |
| 2. | Both assertion and reason are true but the reason is not the correct explanation of the assertion. |
| 3. | Assertion is true but reason is false. |
| 4. | Both assertion and reason are false. |
| Assertion: | Chloride concentration is higher in systemic venous blood than in systemic arterial blood. |
| Reason: | The rise in intracellular bicarbonate in RBCs leads to bicarbonate intake and chloride export. |
| 1. | Both assertion and reason are true and the reason is the correct explanation of the assertion. |
| 2. | Both assertion and reason are true but the reason is not the correct explanation of the assertion. |
| 3. | Assertion is true but reason is false. |
| 4. | Both assertion and reason are false. |
Assertion: The medulla oblongata uses CSF pH as an indicator of blood carbon dioxide concentration.
Reason: Carbon dioxide is the main determinant of the pH of the CSF:
| 1. | Both assertion and reason are true and the reason is the correct explanation of the assertion. |
| 2. | Both assertion and reason are true but the reason is not the correct explanation of the assertion. |
| 3. | Assertion is true but reason is false. |
| 4. | Both assertion and reason are false. |
Given below are two statements: one is labelled as Assertion (A) and the other is labelled as Reason (R):
| Assertion (A): | Particles that are less than 2.5 μm in diameter are the most dangerous for the pathogenesis of occupational lung disease. |
| Reason (R): | The particles of this size move into and out of alveoli, often without substantial deposition and injury. |
In the light of the above statements choose the correct answer from the options given below:
| 1. | Both (A) and (R) are true and (R) is the correct explanation of (A). |
| 2. | Both (A) and (R) are true but (R) is not the correct explanation of (A). |
| 3. | (A) is true but (R) is false. |
| 4. | Both (A) and (R) are false. |
Given below are two statements:
| Assertion (A): | Rarely, emphysema may be caused by the deficiency of the enzyme Alpha 1 antitrypsin deficiency. |
| Reason (R): | Deficiency of alpha-1 antitrypsin leads to a chronic uninhibited tissue breakdown. |
| 1. | Both (A) and (R) are true and (R) is the correct explanation of (A). |
| 2. | Both (A) and (R) are true but (R) is not the correct explanation of (A). |
| 3. | (A) is true but (R) is false. |
| 4. | Both (A) and (R) are false. |