Study the following statements :
a. The substrate binds to the active site of the enzyme.
b. Enzymes isolated form thermophilic organisms get denatured at 50o C.
c. The active site of enzyme breaks the chemical bonds of the product.
d. Prosthetic groups are tightly bound to the apoenzyme.
Select the option which includes all correct statements :
1. (a) & (c)
2. (c) & (d)
3. (b) & (c)
4. (a) & (d)