Ncert Exercises & Solutions

36. Name the site(s) of pyruvate synthesis. Also, write the chemical reaction where in pyruvic acid dehydrogenase acts as a catalyst.

Pyruvate is synthesised in cytoplasm of the cell by the process of glycolysis. 1 molecule of glucose forms 2 molecules of pyruvate through a series of reactions.

Pyruvic acid dehydrogenase catalyses the reaction in which pyruvate forms acetyl Co-A.It requires NAD⁺ , Co-enzyme A and Mg²⁺ ions forits activity. The reaction is as follows

Pyruvic acid + Co - A + {NAD}^{+} \to_{Pyruvate dehydrogenase}^{{Mg}^{2 +}} Acetyl Co - A + NADH + H^{+} + {CO}_{2} ↑

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