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Which of the following cofactors are used during formation of Acetyl-CoA?
(a) CoA, TPP, ${\mathrm{Mg}}^{++}$Mg                      (b) CoA, ${\mathrm{Mg}}^{++}$, ${\mathrm{NAD}}^{+}$
(c) CoA, TPP, NAD+,${\mathrm{NAD}}^{+}$                (d) CoA, TPP, ${\mathrm{NAD}}^{+}$, ${\mathrm{Mg}}^{++}$, Lipoic acid

How many Co2 molecules are formed during formation of two molecules of Acetyl CoA in matrix?
1. 2       
2. 4     
3. 6     
4. 9

Substrate level phosphorylation during TCA cycle occurs:
(a) Once           (b) Twice         (c) 3 times       (d) 6 times

The total number of ATP produced during conversion of succinate to oxaloacetate is
(a) 3       (b) 5       (c) 10      (d) 12

Which is the co-factor of succinic dehydrogenase?
(a) NAD        (b) FAD       (c) NADP    (d) TPP

In Kreb’s cycle, FAD participate as electron acceptor during conversion of
(a) Succinyl Co-A to succinic acid          (b) α- ketoglutarate to succinyl CoA
(c) Succinic acid to fumaric acid            (d) Fumaric acid to malic acid

Mobile carriers of electrons in ETC are
(a) Cytochrome b and Ubiquinone               (b) Cytochrome c and Coenzyme Q
(c) Cytochrome a and Cytochrome ${\mathrm{a}}_3$          (d) FeS complex and Cytochrome ${\mathrm{c}}_1$

How many ${\mathrm{NADPH}}_2$ are produced from the oxidation of one glucose molecule during HMP
path way?
(a) 36    (b) 35    (c) 12    (d) 6

Which intermediate of Kreb’s cycle will effect photosynthesis?
(a) Succinyl CoA      (b) DHAP      (c) PGAL      (d) 1, 3 DPGA

All reaction of TCA cycle occur in matrix of mitochondria except
(a) Oxidation of malate                                (b)Reduction of FAD
(c) Decarboxylation of oxalosuccinic acid       (d) Break down of malic acid

The number of dehydrogenation reaction in TCA cycle is
(a) 1       (b) 2      (c) 3     (d) 4

The complete combustion of glucose, which produces i and ii as end products, yields energy most of which is given out as iii .
          i                     ii               iii
(a) NADH+${\mathrm{H}}^{+}$        ATP          Light
(b) ${\mathrm{CO}}_2$                 ${\mathrm{ \; H}}_2\mathrm{O}$         Heat
(c) ATP                    ${\mathrm{CO}}_2$          Heat
(d) NADH+${\mathrm{H}}^{+}$      ${\mathrm{ \; CO}}_2$          Light

Pick out the incorrect option with respect to glycolysis.
(a) Present in all living organisms.
(b) Glucose undergoes complete oxidation.
(c) Common to both aerobic and anaerobic respiration.
(d) Also called as EMP pathway.

Which statements are true for the fermentation that takes place in yeast?
(i) Pyruvic acid converted into ethanol.
(ii) Takes place in anaerobic conditions.
(iii) Less than 7% of the energy in glucose is released.
(iv) Enzymes involved are pyruvic acid dehydrogenase and alcohol carboxylase.
(v) No CO2 production.
(a) i, ii, iii, v          (b) i, ii, iii
(c) ii, iii ,v             (d) i, ii, iii, iv

Match the following:
i. Complex V             -                 a. NADH dehydrogenase
ii. Complex I             -                 b. Cytochrome bc1 complex
iii. Complex IV          -                 c. ATP synthase
iv. Complex III          -                 d. Cytochrome c oxidase
(a) i-c, ii-a, iii-d, iv-b                 (b) i-b, ii-a, iii-d, iv-c
(c) i-c, ii-a, iii-b, iv-d                 (d) i-b, ii-d, iii-c, iv-a

Name the following:
i. Integral membrane protein complex that forms the channel through which protons cross the inner mitochondrial membrane.
ii. Form of redox-equivalents are removed from PGAL during glycolysis.
iii. Peripheral membrane protein complex that contains the site for ATP synthesis from ADP and inorganic phosphate.
(a) i- ${\mathrm{F}}_0$               ii- Hydrogen atoms         iii- ${\mathrm{F}}_1$
(b) i- ${\mathrm{F}}_1$               ii- Oxygen atom              iii- ${\mathrm{F}}_0$
(c) i- ${\mathrm{F}}_0$               ii- Oxygen molecule         iii- ${\mathrm{F}}_1$
(d) i- ${\mathrm{F}}_1$               ii- Hydrogen atoms          iii-${\mathrm{F}}_0$

Mark true or false.
i. In glycolysis, glucose undergoes partial oxidation to form pyruvic acid.
ii. NADH is oxidized to NAD+ rather slowly in fermentation, however the reaction is very vigorous in case of aerobic respiration.
iii. During oxidation within a cell, all the energy contained in respiratory substrates is not released free into the cell, or in a single step.
(a) i, ii, iii are true                                (b) i is false but ii and iii are true
(c) i and ii are true but iii is false           (d) ii is false but i and iii are true

Find out the incorrect statement.
(a) Fermentation takes place in many prokaryotes and unicellular eukaryotes.
(b) Glycerol enters the respiratory pathway after being converted to acetyl CoA.
(c) The complete oxidation of pyruvate by the stepwise removal of all the hydrogen atoms, leaving molecules of ${\mathrm{CO}}_2$.
(d) Cytochrome c oxidasecomplex contains cytochromes a and ${\mathrm{a}}_3$, and two copper centres

The ATP calculations of respiratory pathway can be made only on assumptions like
(a) None of the intermediates in the pathway are utilised to synthesise any other compound.
(b) Only glucose is being respired – no other alternative substrates are entering in the pathway at any of the intermediary stages.
(c) There is a sequential, orderly pathway functioning, with one substrate forming the next and with glycolysis, TCA cycle and ETS pathway following one after another.
(d) All of these

Link enzyme in cellular respiration is
(a) citrate synthetase                       (b) pyruvate dehydrogenase
(c) isocitrate dehydrogenase             (d) succinyl thiokinase

Oxidation of one molecule of NADH gives rise to
(a) 3 ATP molecules                (b) 12 ATP molecules
(c) 2 ATP molecules                (d) 1 ATP molecule

Which one of the following is the terminal electron acceptor?
(a) Molecular ${\mathrm{CO}}_2$                        (b) Molecular ${\mathrm{O}}_2$
(c) Molecular ${\mathrm{H}}_2$                          (d) ${\mathrm{NADPH}}_2$

The chemiosmotic coupling hypothesis of oxidative phosphorylation proposes that adenosine triphosphate (ATP) is formed because
(a) high energy bonds are formed in mitochondrial proteins
(b) ADP is pumped out of the matrix into the intermembrane space
(c) a proton gradient forms across the membrane
(d) there is a change in the permeability of the inner mitochondrial membrane towards adenosine diphosphate (ADP)

What is the net ATP molecules gain, when 4 molecules of glucose undergo anaerobic respiration in plants?
(a) 8 ATP                     (b) 20 ATP
(c) 144 ATP                  (d) 16 ATP

In photosynthesis, ${\mathrm{NADPH}}_2$ is formed but in respiration it forms during
(a) HMP                          (b) ETS
(c) Krebs' cycle                (d) None of these