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The phase between the two successive M phase is called as
1. Metaphase
2. Anaphase
3. Prophase
4. Interphase

A biosynthetic phase where cell organelle duplicate itself is
1. Interphase
2. Anaphase
3. Prophase
4. Telophase

Yeast can progress through the cell cycle in about
1. 90 sec
2. 90 min
3. 90 hrs
4. 90 yrs

Interphase is called the resting phase because
1. It is the most active phase of the cell cycle
2. There is no apparent activity related to cell division
3. It does not prepare cell for cell division
4. It is the phase where cell rests before entering into mitosis

If the initial amount of DNA is 8 C, then after S phase the amount of DNA would be
1. 4 C
2. 8 C
3. 64 C
4. 16 C

The number of chromosomes in ${\mathrm{G}}_1$ phase is 36, the number of chromosomes in S phase is
1. 36
2. 18
3. 22
4. 37

Major check point of cell cycle is
1. ${\mathrm{G}}_1$ → S transition
2. S → G1 transition
3. ${\mathrm{G}}_2$ → M transition
4. M → G2 transition

${\mathrm{G}}_1$ → S transition is regulated by
1. Cyclins only
2. Cyclin independent kinases
3. Mitotic cyclin and cdc2 kinase
4. ${\mathrm{G}}_1$ cyclin and cdc2 kinase

The morphology of the chromosomes is studied during
1. Metaphase
2. Interphase
3. Prophase
4. Telophase

Decondensation of chromosomes occurs during
1. Prophase
2. Metaphase
3. Anaphase
4. Telophase

If karyokinesis is not followed by cytokinesis, then gives rise to
1. Zygote
2. Fertilised egg
3. Multinucleate condition
4. Embryo

What will be the total number of mitotic divisions in the formation of 64 daughter cells?
1. 6
2. 32
3. 63
4. 16

What will be the amount of DNA in meiosis II products if meiocyte contains 30 pg DNA in G1 phase?
1. 30 pg
2. 60 pg
3. 15 pg
4. 120 pg

Cyclin Dependent Kinases (CDKs)
1. Act as mitotic poisons
2. Cause disassembly of the microtubules
3. Control various phases of cell cycle
4. Arrest cell division due to non-formation of spindle

What is not true about cell cycle?
a. During ${\mathrm{G}}_1$ phase there is active synthesis of RNA and proteins but no change in its DNA content
b. In synthesis or S phase, each chromosome carries a duplicate set of genes
c. During ${\mathrm{G}}_2$ phase, a cell contains double the amount (4C) of DNA present in the original diploid cell (2C)
d. In S-phase a cell doubles the original diploid (2n) chromosome number
1. c & d
2. b & c
3. d only
4. b, c & d

Identify the mismatched pair

1. A – Starts with karyokinesis and ends with cytokinesis
2. B – Stage where cells are inactive metabolically
3. C – Cell grows and carries out normal metabolism
4. D – Period of cytoplasmic growth

Chromatin fibres duplication, Genetic material - 4C, Histone protein synthesis, Membranous organelle duplication, DNA replication, centriole duplication.
How many of the above features are associated with synthesis phase of cell cycle?
1. Three
2. Five
3. Four
4. Six

How many generations are required by a cell of meristem to produce 128 cells?
1. 127
2. 64
3. 32
4. 7

Phragmoplast is formed by golgi complex and grows
1. Centripetally to form cell plate
2. Centrifugally to form cell plate
3. Centripetally to produce a cleavage furrow
4. Centrifugally to form a cleavage furrow

Select an incorrect statement with respect to metaphase
1. Spindle fibres are attached to small disc shaped structures at the surface of centromeres called kinetochores
2. The plane of alignment of the homologous pair of chromosomes at metaphase is referred to as the metaphasic plate
3. Chromosome appears to be made up of two sister chromatids
4. The size of chromosomes can be studied in this phase
 

Best stages to study morphology and shape of chromosome are respectively
1. Metaphase, Telophase
2. Prophase, Anaphase
3. Telophase, Anaphase
4. Metaphase, Anaphase

All are the essential stages that take place during meiosis, except
1. Two successive divisions without any DNA replication occuring between them
2. Formation of chiasmata and crossing over
3. Segregation of homologous chromosomes
4. Number of chromosomes in daughter cells after meiosis II is reduced to half but the amount of DNA remains the same

To produce 102 pollen grains, how many meiotic divisions are required?
1. 25
2. 25.5
3. 26
4. 27

Which of the following options gives the correct sequence of events during mitosis?
1. Condensation → nuclear membrane disassembly → crossing over → segregation → telophase
2. Condensation → nuclear membrane disassembly → arrangement at equator → centromere division → segregation → telophase
3. Condensation → crossing over → nuclear membrane disassembly → segregation → telophase
4. Condensation → arrangement at equator → centromere division → segregation → telophase

Anaphase promoting complex (APC) is a protein degradation machinery necessary for proper mitosis of animal cells. If APC is defective in a human cell, which of the following is expected to occur?
1. Chromosomes will not condense
2. Chromosomes will be fragmented
3. Chromosomes will not segregate
4. Recombination of chromosome arms will occur

When cell has stalled DNA replication fork, which checkpoint should be predominantly activated?
1. ${\mathrm{G}}_1$/ S
2. ${\mathrm{G}}_2$ / M
3. M
4. Both ${\mathrm{G}}_2$ / M and M

Match the stages of meiosis of Column-I to their characteristic features in Column-II and select the correct option using the codes given below:
     Column-I                                       Column-II 
a. Pachytene                     (i) Pairing of homologous chromosomes
b. Metaphase I                  (ii) Terminalization of chiasmata
c. Diakinesis                     (iii)Crossing-over takes place
d. Zygotene                      (iv) Chromosomes align at equatorial plate
1. a(iii), b(iv), c(ii), d(i)
2. a(i), b(iv), c(ii), d(iii)
3. a(ii), b(iv), c(iii), d(i)
4. a(iv), b(iii), c(ii), d(i)

A cell at telophase stage is observed by a student in a plant brought from the field. He tells his teacher that this cell is not like other cells at telophase stage. There is no formation of cell plate and thus the cell is containing more number of chromosomes as compared to other dividing cells. This would result in
1. Polyteny
2. Aneuploidy
3. Polyploidy
4. Somaclonal variation

The enzyme recombinase is required at which stage of meiosis
1. Pachytene
2. Zygotene
3. Diplotene
4. Diakinesis

Given below is the representation of a certain event at a particular stage of a type of cell division. Which is the stage ?

1. Prophase of Mitosis
2. Both prophase and metaphase of mitosis
3. Prophase I during meiosis
4. Prophase II during meiosis

During mitosis ER and nucleolus begin to disappear at
1. Early prophase
2. Late prophase
3. Early metaphase
4. Late metaphase

At what stage of the cell cycle are histone proteins synthesized in a eukaryotic cell ?
1. During entire prophase
2. During telophase
3. During S-phase
4. During G2 stage of prophase

How many chromosomes will the cell have at ${\mathrm{G}}_1$, after S and after M phase respectively, if it has 14 chromosomes at interphase?
1. 14, 14, 7
2. 14, 14, 14 
3. 7, 7, 7
4. 7, 14, 14

Each chromosome at the anaphase stage of a bone marrow cell in our body has
1. Two chromatids
2. Several chromatids
3. No chromatids
4. Only one chromatid

Colchicine is an inhibitory chemical, which
1. Stops the functioning of centriole
2. Prevents attaching of centromeres with rays
3. Prevents the spindle formation in mitosis
4. Prevents the formation of equatorial plane

A bacterium divides every 35 minutes. If a culture containing 105 cells per ml is grown for 175 minutes, what will be the cell concentration per ml after 175 minutes?
1. 35 × ${10}^5$ cells
2. 32 × ${10}^5$ cells
3. 175 × ${10}^5$ cells
4. 85 × ${10}^5$ cells

A gymnospermic leaf carries 16 chromosomes. The number of chromosomes in its endosperm will be
1. 12
2. 8
3. 16
4. 24

Crossing over that results in genetic recombination in higher organisms occurs between
1. Sister chromatids of a bivalent
2. Non-sister chromatids of a bivalent
3. Two daughter nuclei
4. Two different bivalents